Neuro-Infectious Diseases

Viral and immune mediated disorders of the nervous system are among the foremost difficult neurological disorders. The most common neuroimmune disorder is multiple sclerosis; and HIV is the most common viral infection of the nervous system. Common to disorders is the progressive loss of neurons, resulting in significant cognitive and motor dysfunction. The brain is a direct target for certain infections, and may also be indirectly affected by systemic bacterial, viral, or parasitic infections. Certain pathogens, like the human immunodeficiency virus (HIV), syphilis, West Nile Virus, Borrelia burgdorferi (resulting in Lyme disease), and other viral brain infections occur in healthy persons. Other infections, such as fungal infections or rarer parasites tend to most commonly affect people with reduced immune systems from cancer, chemotherapy, immunosuppressive therapy, or transplantation. Several infectious diseases can affect the brain, spinal cord, peripheral nerves, neuromuscular junction (the connection between the nerve ending and the muscle), or the muscles.

  • Encephalitis
  • Meningitis
  • HIV
  • Neurotoxicity

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